Gremio know who they could face in the next round of the Copa Libertadores. The group winner will face Penarol and the runner-up will take on Fluminense.
Gremio earned qualification to the knockout stages of the Copa Libertadores last time out with a 1-0 victory over Huachipato thanks to a first-half goal from Diego Costa. They know a victory here would see them top the group.
Estudiantes have nothing to play for but pride coming into this game as they sit bottom of the group, four points adrift of the nearest team. They are winless in their last three matches in all competitions, On Sunday, they drew 1-1 at home with Godoy Cruz.
The earlier meeting between these sides saw Gremio run out 1-0 winners in Argentina.